Asia-Pacific (excluding Japan): Dominates production and consumption with increasing use in supplements, cosmetics, and functional foods across China, India, and Southeast Asia
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When traditional methods like diet and exercise arent enough, many people look toward medical interventions like Wegovy (semaglutide) or phentermine
However, in OA, M2 numbers are limited and may shift toward an M1-like phenotype under sustained inflammatory stimuli, reducing their capacity to maintain iron homeostasis (109, 110).Together, these insights support the hypothesis that iron metabolism in M1 macrophages not only contributes to ferroptosis susceptibility in OA, but also represents a potential immunometabolic checkpoint for therapeutic intervention
These drugs are used to treat diabetes and are classified as GLP-1 RAs (receptor agonists), also known as agonists GLP-1 RAS or peptide 1 receptor agonists