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One of the most common side effects we see with ozempic is GI distress due to slowed gut motility

EBioMedicine 52, 102626

After a single subcutaneous dose of the GLP-1R agonist semgalutide (30 nmol/Kg), mice were given free access to water but no food or ethanol

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These agents are believed to suppress presynaptic dopamine release and dampen postsynaptic reward signaling at mesolimbic synapses, thereby diminishing the reinforcing effects of alcohol consumption