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Retatrutides data primarily stems from Phase 2 trials published in late 2023 and ongoing Phase 3 TRIUMPH trials

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% relative survival was normalized to vehicle controls (FT282-CCNE1: n = 4/group, Ovcar8-CCNE1, n = 3/group

The autophagy-related gene 14 (Atg14) is regulated by forkhead box o transcription factors and circadian rhythms and plays a critical role in hepatic autophagy and lipid metabolism