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There was also a pronounced and dose-dependent effect on body weight gain

This timeline covers what the clinical and preclinical evidence shows at each stage, what community reports consistently describe, and the factors that determine whether results land on the faster or slower end of the spectrum

However, since a diagnosis of apoptosis implies a specific sequence of biochemical and morphological events and should ideally be supported by electron microscopy, it may be more prudent to diagnose single cell necrosis unless there is definitive proof of apoptosis provided by electron microscopy (Levin et al