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GLP-1 contributes to increases in PGC-1alpha expression by downregulating miR-23a to reduce apoptosis

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The catch: no published, peer-reviewed human randomized controlled trial exists for BPC-157 as of March 2026

WADA placed it on a list called S0: "Non-Approved Substances" the category for anything that no health authority anywhere in the world has approved for use in humans

Grapefruits deserve special mention because research suggests they may have mild metabolic benefits, though you should confirm with your PlexusDx provider if you're taking other medications, as grapefruit can interact with certain compounds