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In addition to these roles, GLP-1R activation has been demonstrated to exert antifibrotic effects on the fibrosis of solid organs, including the heart, liver and kidneys [25]
(2021) 9:e001341
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Therefore, the research and development of the relevant drugs and the replacement therapy of double GIP-GLP-1R agonists (e.g., tirzepatide) and triple GIP-GCG-GLP-1R (e.g., peptide 20) agonist are key research fields
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