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doi: 10.1016/j.cmet.2013.04.008 136 WangBZhongJLinHZhaoZYanZHeHet al
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Clinical Indicators for Switching: Response, Tolerance, and Efficacy Profiles Healthcare providers consider several factors when evaluating whether a switch is appropriate: inadequate weight loss response at maximum tolerated dose, gastrointestinal side effects that limit dose escalation, or a need for enhanced metabolic impact
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