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Caution is advised in patients with Leber optic atrophy, a genetic disorder caused by chronic cyanide intoxication (such as from smoking, alcohol or some plants), against the use of cyano-B12 due to its cyanide moiety, whilst hydroxo-B12 is a cyanide antagonist and can therefore be used in these patients
It might be helpful for some, but for me, its not showing significant changes." Source: Reddit - r/Fitness 3
The most common side effects are mild and transient: water retention, tingling or numbness (most often in the hands), and occasional fatigue or headache shortly after injection
Chronic conditions (tendonitis, joint issues): Typically requires 48 weeks of consistent use to see substantial improvements, with continued benefits over 12+ weeks
Scheduling a series of repeat appointments is also inconvenient
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