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If you stop for several weeks and then restart at your previous maintenance dose, you will likely experience the same nausea, vomiting, and diarrhea that prompted the original gradual titration

By activating your GLP-1 and GIP receptors, tirzepatide enhances insulin secretion in response to food, slows gastric emptying (which leads to increased feelings of fullness), and reduces hunger

Complementary Mechanisms of Action SGLT2is and GLP-1RAs lower blood glucose levels through distinct yet complementary pathways

Skin-related reactions are also common, including irritation, redness, itching, or allergic responses from the adhesive or active ingredients in the patch

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