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coli DH5 was transformed with pECXT99A-based plasmids harboring the dehydrogenases TMABADH.1S, TMABDH.1, or TMABADH.2 (Supplementary Table 1) and with pECXT99A as the empty vector control

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Proper GLP 1 therapy requires a clinical assessment that includes review of cardiovascular risk, kidney function, thyroid history, and current medications before starting treatment

A dominant-negative human G s (DNG s ) with 8 mutations (S54N, G226A, E268A, N271K, K274D, R280K, T284D, and I285T) was generated as previously described to limit G protein dissociation 51