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In these cases NAC is acting as a precursor to cellular cysteine, which is itself converted into a powerful antioxidant molecule called glutathione (GSH)
375 However, PROTACs face translational challenges due to poor membrane permeability, instability, suboptimal pharmacokinetics, uneven tissue distribution, and limited specificity
Sesamin, sesamol, and sesaminol are phenolic compounds present in sesame seeds and oil, known for antioxidant and anti-inflammatory properties (65)
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A recent study reported that human microbiota also interacts directly with the host through metabolites 12
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