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IGF1 Deficiency, Recombinant Human Insulin-Like Growth Factor (rhIGF-1) Treatment of Short Stature Associated with IGF-1 Deficiency

Increasing growth hormone and IGF-1 levels may carry potential risks, including worsening insulin resistance in some individuals and, theoretically, stimulating the growth of existing cancers

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For depression, a meta-analysis of randomised and cohort data reported a statistically significant reduction in depression scores among GLP-1R agonist users relative to controls [15]