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DEM exposure resulted in a clear accumulation of Keap1-GFP in cytoplasmic autophagosomal foci, an accumulation of Nrf2-GFP in the nucleus and an accumulation of Srxn1-GFP in the cytoplasm, which is in agreement with the current qualitative understanding of the Nrf2 pathway
Metabolic and Hormonal Adjustments Weight loss and changes in blood sugar regulation can alter hormonal and metabolic signals that influence the hair cycle
Additionally, heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1), an RNA-binding protein, induces the alternative splicing of PKM2 [152]
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Excess body fat, particularly around the abdomen, increases insulin resistance
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