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In certain neurological disorders, T lymphocytes can infiltrate the CNS by crossing the BBB, where they exacerbate neuroinflammatory responses through pro-inflammatory cytokine release and glial cell activation
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What started as a class of medications for type 2 diabetes moved into weight loss, and has since expanded into treating fatty liver disease (also known as metabolic dysfunction-associated steatohepatitis, or MASH), specific cardiovascular diseases, obstructive sleep apnea, and the list continues to grow
Smith, S.R., et al
You have severe gastrointestinal conditions, such as gastroparesis
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