anhedonia glp-1 People Can Lose Their Zest for Life After Starting GLP-1s, Docs Warn TheCut just released an article

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When brain glutathione is depleted, the delicate neuronal lipid membranes undergo lipid peroxidation, and the protective blood-brain barrier becomes compromised

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Of note, a small number of cases of acute pancreatitis associated with GLP-1RA use have been reported in clinical trials: 38 cases in 17,775 patient-years of exposure compared with 9 events in 5863 patient-years of exposure with the comparator treatment

The informed consent aims to protect both the patient and the provider legally by documenting patient choices and understanding