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doi: 10.1007/s12020-012-9739-3

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They can cause some side effects, like an upset stomach or diarrhea, and rarely, more serious issues like pancreatitis or thyroid problems

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We found that this was true even at the pre-leukemic stage, and furthermore, that key genes involved in ameliorating oxidative stress and regulating DNA damage response are detrimentally affected with reduced translation efficiency (including Gpx1, Otud4, Smarca2, Fance, and Tlk1 , amongst others)

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In human adipocytes, tirzepatide exposure results in an increase in both mRNA expression and LPL activity, as well as increased fatty acid uptake into adipocytes

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