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Medications including metformin, proton pump inhibitors, and H2-receptor antagonists may reduce absorption of B12, potentially prolonging the time to clinical improvement
Continuing to inject past this point wastes product
Instead, it is active within mitochondrial functions
Pharmaceutical companies already at the forefront of GLP-1RA development have benefitted from this, while others are making significant investments to enter the weight-loss drugs market
Presented for research literature review only Rosen CJ (2025)
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