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Reprinted with permission from The Annals of Pharmacotherapy www.theannals.com GLUTATHIONE IN HEALTH AND DISEASE: PHARMACOTHERAPEUTIC ISSUES Ben M Lomaestro and Margaret Malone OBJECTIVE : To review the current research and importance of glutathione (GSH) therapy in health and disease and to provide a basic overview of the widespread use and interest in this compound

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Future studies using other transgenic mouse models will be useful in determining the exact path-way by which paracetamol causes liver damage and may therefore provide novel therapeutic strategies by which to reverse liver damage in patients who present late after paracetamol overdosage

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