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Glutathione (GSH) is the major free radical scavenger in the brain, lower levels of this antioxidant elevate cellular vulnerability to oxidative stress
somatostatin analogues directly antagonise GHRH-receptor signalling and reduce ghrelin-receptor sensitivity through hypothalamic mechanisms
One of the hypothesized reasons is the existence of an extra copy of amyloid precursor protein (APP) gene located on chromosome 21
While injections are a common method of administering Vitamin B12, there are alternative options available, such as oral supplements and nasal sprays
Cobalamin deficiency results in the decrease of this conversion, resulting in high plasma levels of homocysteine, which is associated with a higher risk of cerebrovascular disease, depression, dementia, cellular stress, and apoptosis (25, 27, 64, 70)
