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Maybe the spike is due to increased medical surveillance rather than the drug itself directly causing cancer

Glucose-lowering drugs that stimulate insulin secretion Glucose-lowering drugs that stimulate insulin secretion Sulfonylureas: Sulfonylureas are classified as insulin secretagogues and their primary mechanism of action is to stimulate pancreatic beta cells to secrete insulin, effectively lowering blood glucose levels

The FDA determined the tirzepatide shortage resolved in late 2024 and the semaglutide shortage resolved in February 2025, and it set enforcement deadlines through 2025 for compounders to wind down shortage-based production

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These effects may range from mild to severe, similar to those seen with FDA-approved versions