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A complete medical history, including cardiovascular risk factors, thyroid disease, pancreatitis history, and current medications, is essential before considering GLP-1 agonist therapy
More specifically it has been posited to regulate the cellular actin-cytoskeleton and cellular migration by sequestering G-actin
Here are 8 potential reasons why not to prescribe Lixisenatide: 1- this is only one small study and only one dose was tested, 2- Lixisenatide is not currently available at pharmacies, 3- the weight loss associated with this GLP-1 is not desirable in many cases of Parkinsons disease where weight loss is an issue, 4- non-motor outcomes did not change as in other trials, and this will need to be better explained
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