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However, mitochondrial dysfunction can lead to a buildup of ROS due to an imbalance in their production and degradation 4,5 Another major source of ROS is NADPH oxidase (Nox), a membrane-bound enzyme complex that produces superoxide by transferring an electron to oxygen from NADPH

A specific interest is placed on neuropeptide-mediated regulation of mucus secretion and their effects on the expression of the two major secreted gel-forming mucins in the airway, mucin5AC (muc5AC) and mucin5B (muc5B) [20]

Some alternatives may have different potency, stability, or side effect profiles

Researchers also hypothesize that the two molecules may exhibit synergistic effects in the healing process when exposed in combination

For patients with neurological involvement, maintenance injections are typically given every 2 months