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A meta-analysis of clinical trials, including data from Novo Nordisk itself, found higher incidence of optic ischemic neuropathy in GLP-1 groups compared to placebo

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First, proteins containing N-methylated lysine residues are degraded by lysosomes or proteasomes to release 6-N-trimethyllysine (TML), in which lysine provides the carbon backbone and nitrogen atom of carnitine, whereas methionine provides the methyl group

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