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However, aramchol did not meet the primary endpoint a significant reduction of IHL of the phase II trial
Mangalhara, K
The results showed that SAC significantly reduced the inflammatory response caused by gluten digestion products, decreasing the expression of inflammation-related proteins and mRNA such as XPO1, NFB, and IL8
After 24 h, the transfected cells were seeded onto 384-well microtiter plates (3000 cells per well) in HBSS supplemented with 5 mM HEPES, 0.1% (w/v) bovine serum albumin (BSA) and 0.5 mM 3-isobutyl-1- methylxanthine, and stimulated with increasing concentrations of GLP-2 for 30 min at RT
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