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Compounded semaglutide is still a subcutaneous injection, but is handled using syringes instead of spring-loaded devices
In this setting, daily administered GLP-1RAs added to basal insulin provides a less relevant improvement in glycemic control ( HbA 1c = -0.68%, 95% CI -0.92
Potentially alter when it is absorbed and in what part of the gut
This independent review sorts that out
Both are GLP-1 receptor agonists used for weight management
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/profile/Asfandyar-Sheikh/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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