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Gao K, Mu CL, Farzi A, Zhu WY

Slightly elevated risk of urinary tract infections (UTIs) in female patients: Extremely rapid weight loss alters hormonal and fluid balance, contributing to marginally higher UTI incidence relative to patients receiving semaglutide

Animal As a senolytic, FOXO4-DRI carries mechanism-specific theoretical risks discussed in the senescence literature including disruption of beneficial senescence surveillance and off-target effects on stem-cell populations that share features with senescent cells and senolytic translation from mouse to human has a history of failures

It may be related to the dose of the toxic drug used or the period of study observation.However, most of the current research results support the antioxidant stress effect of GPX1, so GPX1 is an important antioxidant in mammals