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Clinical Context Relevant to GLP-1 Treatment Discussions in 2026 GLP-1 receptor agonists like semaglutide represent a class of medications originally developed for type 2 diabetes management that have demonstrated meaningful effects on weight management in clinical research
This condition is more common in older adults, in part because levels of hormones that help protect muscle including sex hormones, growth hormone, and related growth factors tend to decline with age, says Michael Schwartz, MD, a researcher and professor of medicine, metabolism, endocrinology, and nutrition at UW Medicine in Seattle
Because GLP-1s suppress appetite, a history of restrictive eating changes the plan, and we screen for it before prescribing
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