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While insomnia is not a commonly reported side effect in clinical trials, individual experiences vary
They are usually mild and temporary
[1] [3] Whilst these mechanisms contribute to improved glycaemic control and weight reduction, they also account for one of the most commonly reported adverse effects: nausea
RAGE engagement triggers NFkB, leading to generation of reactive oxygen species with mitochondrial dysfunction in both podocytes and endothelial cells, fostering inflammation and fibrosis
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