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Both tirzepatide and semaglutide were associated with increased risk of gastrointestinal adverse events compared with placebo at all doses, tirzepatide 15mg was associated with the highest risk for nausea (3.6 times), vomiting (4.4 times) and diarrhoea (2.0 times)
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Why the conversion is not exact Tirzepatide is not just "stronger semaglutide." It is a different type of medication with a different receptor profile
The Bottom Line TRIUMPH-4 establishes retatrutide as the most potent pharmacological weight loss agent ever tested in a Phase III program
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