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La falta de esta molcula tambin puede deberse a componentes genticos que provocan problemas en su sntesis, malabsorcin intestinal o problemas hepticos

J Neurol

PMID: 12851303 Reported G s / cAMP signalling cAMP elevation via class A GPCR coupling Tao (Endocr Rev 2010) reviewed melanocortin-4 receptor pharmacology, summarizing studies on the MC4R, from its cloning and tissue distribution to its physiological roles across multiple body systems