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They were originally developed to treat type 2 diabetes, but clinicians observed that many patients also experienced significant weight loss
PT-141 typically takes effect within 30-60 minutes of subcutaneous injection
Some patients in earlier trials also discontinued retatrutide because they felt they were losing too much weight
J Biol Chem (2008) 283(13):872335.10.1074/jbc.M706105200 45 WinklerDGSutherlandMKGeogheganJCYuCHayesTSkonierJEet alOsteocyte control of bone formation via sclerostin, a novel BMP antagonist
Pancreatitis and gallbladder disease are recognised safety signals associated with the GLP-1 receptor agonist class
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