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Epidural injections in prevention of surgery for spinal pain: systematic review and meta-analysis of randomized controlled trials
Most people dont have problems with B12 shots, but some might feel pain or redness at the site, have diarrhea, or itch
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The follow-up pivotal trial (METAOD006 / OPTIONS) enrolled a larger cohort and failed to replicate statistically significant weight loss, which led Metabolic Pharmaceuticals to halt the formal drug development program in 2007
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