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Animal studies further indicate that chronic paternal exposure to anabolicandrogenic steroids prior to conception may alter sperm-borne epigenetic signatures and adversely affect fertility-related outcomes in offspring, although direct evidence in humans remains limited and requires further investigation (80)
Once absorbed into the circulation, SCFAs serve as energy substrates, influence the maturation of microglia in the CNS, and act as CNS signaling molecules [12, 14]
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