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Understanding the functions of genes on chromosome 21 and their impact on cognitive impairment is of paramount importance (Ishihara and Akiba 2017)
The novel dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 (GLP-1) receptor agonist tirzepatide transiently delays gastric emptying similarly to selective long-acting GLP-1 receptor agonists
The problem is not the medication alone
This result suggested they might be recognizing nontarget features, such as the GGS linker between lysozyme and RNAP, rather than authentic substrate residues
10.1152/physrev.00013.2014 22 SmeekensS
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