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A 2025 study from the University of Utah raised additional questions, finding that while skeletal muscle mass loss may be less than expected in some patients, muscle strength and function may decline even when mass appears preserved full details available via University of Utah Health: New study raises questions about how Ozempic affects muscle size and strength
Overall, GLP-1 receptor agonists weight loss effects seem to arise from reducing peoples food intake
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The critical difference: tirzepatide side effects are almost entirely gastrointestinal and typically improve with time, while phentermine side effects include cardiovascular concerns that persist and require ongoing monitoring
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