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Serious risks reported with GLP-1 therapy include pancreatitis, gallbladder problems, low blood sugar (particularly alongside other diabetes medicines), kidney issues from dehydration, and allergic reactions
The Contrave titration, or dose-escalation, is a four-week schedule
At any rate, this cluster of adverse events was experienced by 22.9% of the 7.2mg group versus 6% of the 2.4mg group (it was not an adverse event at all in the original STEP 1 trial at all.) The researchers claim that Dysaesthesia adverse events were mild for most participants who experienced them: and that Most participants recovered from the event by the end of the trial. Of course we dont know if they will come back and for those who hadnt recovered, we dont know how this impacts their life/quality of life
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Once in a liquid state, the peptide is highly sensitive to thermal degradation
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