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These conditions can cause severe abdominal pain, nausea, fever, and digestive problems, and often require surgery to remove the gallbladder

It is also the most satiating macronutrient, meaning it keeps you feeling full longer than carbs or fats

Another important miRNA regulating cell metabolism is miR-378/378*, embedded within gene encoding peroxisome proliferator-activated receptor gamma coactivator 1-beta (PGC-1), a transcriptional regulator of oxidative energy metabolism

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Separate application times or buffering agents can mitigate this