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BPC-157 stimulates expression of EGR-1 gene responsible for cytokine and growth factor generation and early collagen formation, while also inducing NAB2 expression to regulate the extent of tissue response
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Finally, they reflect pathways likely additional to those involved in the angiogenesis (Vukojevic et al., 2018), recently associated in particular with the increased expression, internalization of VEGFR2, and the activation of the VEGFR2-Akt-eNOS signaling pathway ( Genes Expression as Support ), given the rapid presentation of all of these effects, which occurred before the process of angiogenesis could be initiated (Sikiric et al., 1993
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