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Hater N, Iwaniuk KM, Leifeld C, Grten P, Wiek C, Raba K, et al
More importantly, SOD has a very high solvent deuterium KIE, due to a proton-coupled electron transport mechanism
That experience reinforced an important point: two bottles with similar Supplement Facts panels may not represent the same manufacturing quality
While this approach has been used to predict the membrane permeability of drug molecules 11,12,13 , it cannot reveal transport mechanisms or provide a trajectory of a permeating molecule across the bilayer, which are desirable information for pharmacophore optimisation
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