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Research suggests that up to 90% of individuals with idiopathic PN may have undiagnosed prediabetes, emphasizing the critical role of considering prediabetes in the diagnostic process [8]

Lee, Molecular and Cellular Biology, DOI: 10.1158/1538-7445.AM2020-1239 Published August 2020

A level which is sustained below 140 pmol/L will ultimately result in megaloblastic anaemia (or Pernicious Anaemia (PA)), in which there is reduced quality and number of red blood cells

Higher concentrations shift this balance

The use of these proteins would be based on their expected biological activity: DSIP as the active peptide expected to induce sleep, and CBBBP to facilitate entry into brain