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Intranasal delivery offers powerful advantages for CNS-targeted therapies, providing non-invasive blood-brain barrier bypass with rapid onset and enhanced patient compliance
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The first evidence of the exploitation of this route was obtained by Sjlinder and Jonsson in human CD46 transgenic mice (Sjlinder and Jonsson, 2010)
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Current research suggests that probiotic supplementation may facilitate weight management and improve cardiometabolic parameters (418)
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