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Probiotics The gut microbiome plays a significant role in metabolism, immune function, and even mood regulationall areas potentially affected by GLP-1 medications and rapid weight loss

What raises concerns are some of the recent reports of serious ADRs associated with GLP-1RAs: (i) Pfizers disclosure of elevated aminotransferases in users of lotiglipron (a novel oral GLP-1RA) is indicative of hepatocellular injury [11]

Body-compositionassociated signaling explore how metabolic pathways influence markers tied to tissue composition, substrate allocation, and structural balance within experimental models

doi: 10.2337/cd19-0079 26 NauckMAStewartMWPerkinsCJones-LeoneAYangFPerryCet al

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