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The sections that follow apply this framework to specific physiological domains, beginning with metabolic and energy-balance peptides beyond the incretin family
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Treatment with PPP antagonists, dehydroepiandrosterone (DHEA) and 6-aminonicotinamide (6-AN), restored the phagocytic capacity of Dicer-KO macrophages to WT levels and mitigated the inflammatory response during efferocytosis (Mao et al., 2021) (Figure 2B)
Nevertheless, the clinical implications of high GH and low IGF-I on long-term metabolic and vascular outcomes in patients with T2D remain unclear
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