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However, this appears to be the exception rather than the rule
The 7.5mg and 12.5mg intermediate doses were included in clinical protocols as transitional steps to improve tolerability but were not separate study arms in SURMOUNT-1
Under high glucose conditions, endothelial cells can acquire the characteristics of fibroblasts, via endothelial-mesenchymal transition (EndMT), which can contribute to neointimal hyperplasia [47]
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