All clinical trial data and research findings presented on this page are sourced from peer-reviewed journals and official publications
Certain medications The following drugs can reduce levels of vitamin B12 in your body: Antibiotics -- long-term use can lower vitamin B levels generally Anti-seizure drugs Chemotherapy medicines, especially methotrexate Drugs used to reduce stomach acid, like H2 blockers (Pepcid AC, Tagamet, Zantac) and proton pump inhibitors (Nexium, Prevacid, Prilosec) Metformin (Glucophage) -- taken for diabetes Colchicine -- taken for gout Some cholesterol-lowering medications Other causes You're over 65
Educating patients on when to pause or discontinue therapy is critical for preventing complications and maximizing clinical benefit
References Tesamorelin LiverTox: Clinical and Research Information on Drug-Induced Liver Injury National Institutes of Health, NIDDK (2018) Tesamorelin (Subcutaneous route) Drug Information Mayo Clinic / IBM Merative (2025) Effects of tesamorelin (TH9507), a growth hormonereleasing factor analog, in HIV-infected patients with excess abdominal fat: a pooled analysis of two phase 3 trials J
B is crucial for the metabolism of fats, drugs, and steroids and for the activation of other vitamins (it helps convert vitamin B to its active form and aids the conversion of tryptophan to niacin)