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enhances skeletal muscle glucose uptake (Solomon et al., 2013) Metformin : activates AMPK , reduces hepatic glucose output
Nausea is a common complaint
However, the convenience of a single morning dose means most researchers prefer once-daily administration, and the clinical data supporting split dosing specifically for AOD 9604 is limited
Exact figures for PA are difficult due to inconsistent diagnostic thresholds, imperfect tests, and under-recognition
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