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Wegovy is specifically for people with a body mass index (BMI) of 30 or more, or 27 or more with weight-related health conditions, including prediabetes and high blood pressure

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Most practitioners check B12 levels at 3-6 months after initiating tirzepatide and then every 6-12 months during maintenance

Emerging therapeutic strategies aim to target these pathways specifically like MATs, NOX inhibitors, and Nrf2 activators, though clinical success has been limited by off-target effects and the dual role of ROS in physiological signaling (Pergola et al., 2021)