Patients who have undergone gastric banding should be aware of the following signs that may indicate falling B12 levels and warrant prompt blood testing: Neurological symptoms: Tingling, numbness, or 'pins and needles' in the hands or feet Difficulty with balance or coordination Memory problems, difficulty concentrating, or 'brain fog' Mood changes, including low mood or irritability Haematological symptoms: Persistent fatigue or weakness disproportionate to activity levels Breathlessness on mild exertion Pallor or a slightly yellowish tinge to the skin Other indicators: A sore, smooth, or inflamed tongue (glossitis) Mouth ulcers occurring frequently It is important to recognise that some of these symptoms particularly fatigue and low mood are non-specific and may overlap with other post-operative nutritional deficiencies, such as iron or vitamin D deficiency

How long the injection lasts depends on several factors: How severe the deficiency is A persons age and how fast their body processes things Problems with digestion or absorbing nutrients Daily habits or activity levels How often does the body use B12 inside its cells People with pernicious anemia or ongoing deficiency often get weekly shots, while others do fine with a monthly injection
While animal studies provide robust data, human pharmacokinetic profiles are less defined, with ongoing research exploring its full pharmacological behavior
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But concentrated solutions (10mg/ml or higher) should display obvious blue coloration