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After administration of JANUMET XR with a high-fat breakfast, the AUC for metformin increased 62%, the Cmax for metformin decreased by 9%, and the median Tmax for metformin occurred 2 hours later relative to the fasted state

Links mentioned in this episode Perimenopause weight loss plan Insulin resistance episode: what labs to check Perimenopause weight loss episode Two-part sleep series (why sleep shifts appetite, cortisol, and metabolic health): Part 1, Part 2 Thyroid deep dives with McCall McPherson (thyroid panels and GLP-1 considerations)

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Studies published in JAMA Network confirm that bariatric surgery significantly reduces the risk of heart failure, stroke, and hypertension in obese individuals with Type 2 diabetes

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