can semaglutide be out of the fridge Does compounded need to refrigerated? Does Ozempic need to be

Large-scale randomized controlled trials such as SUSTAIN, SELECT, and SURPASS, as well as multiple realworld cohort studies, have consistently reported no significant increase in the risk of depression, suicidality, or psychiatric hospitalization compared with placebo or other anti-diabetic agents [110-112]

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Polyphenol-rich foods like berries, apples, asparagus, dark chocolate, and walnuts

To protect muscle during treatment: Encourage strength training and physical activity Ensure adequate protein intake Use tools to monitor body composition, not just weight This helps patients maintain functionality while still achieving the metabolic benefits of treatment

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